Early Rehabilitation Nursing for Severe Acute Pancreatitis (NCT07076316) | Clinical Trial Compass
CompletedNot Applicable
Early Rehabilitation Nursing for Severe Acute Pancreatitis
China104 participantsStarted 2021-02-01
Plain-language summary
This randomized controlled trial evaluates the clinical efficacy of a structured early rehabilitation nursing (ERN) pathway compared to routine care in patients with severe acute pancreatitis (SAP). The study aims to determine if the ERN pathway, which includes phased mobility, respiratory training, and psychological support, can improve gastrointestinal recovery, reduce hospital stay and complications, and enhance functional independence and quality of life.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosis of Severe Acute Pancreatitis (SAP) according to the Revised Atlanta Classification.
* APACHE II score \> 8.
* Expected ICU stay ≥ 14 days.
* Hemodynamic stability (mean arterial pressure ≥ 65 mmHg for \> 24 hours).
* Provided informed consent.
Exclusion Criteria:
* Presence of chronic metabolic disorders (e.g., end-stage renal disease, cirrhosis).
* Coagulopathy (INR \> 1.5 or platelet count \< 50×10⁹/L).
* Cognitive impairment hindering cooperation with the rehabilitation protocol.
* Recent use of antiplatelet or anticoagulant medication (within 7 days).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Time to Relief of Abdominal Distension
Timeframe: From randomization up to hospital discharge (an average of 14 days)
2
Time to First Bowel Movement
Timeframe: From randomization up to hospital discharge (an average of 14 days)
3
Duration of Hospital Stay
Timeframe: From hospital admission up to hospital discharge (an average of 14 days)
4
Incidence of Complications
Timeframe: From randomization until hospital discharge (an average of 14 days)