RecruitingNot Applicable

Neutrophil to Lymphocyte Ratio and Postdural Headache

Turkey (Türkiye)821 participantsStarted 2025-07-12

Plain-language summary

This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women aged 18 years or older * Underwent elective or emergency cesarean section under spinal anesthesia * Had complete preoperative complete blood count (CBC) data available * No known hematological or inflammatory disease * No intraoperative complications recorded * Medical records accessible for postoperative follow-up regarding PDPH symptoms Exclusion Criteria: * Age under 18 * Absence of preoperative complete blood count data * Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy * Platelet count \<150,000/mm³ or INR \>1.5 * Incomplete or missing medical records

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postdural Puncture Headache (PDPH) incidence

Timeframe: Within 10 days postoperatively

Trial details

NCT IDNCT07075874

SponsorIstinye University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-07-15

Contact for this trial

ilke dolgun

+905555485632 ilkeser2004@gmail.com

View on ClinicalTrials.gov More Preoperative Neutrophil-to-Lymphocyte Ratio (NLR) trials