Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy (NCT07075731) | Clinical Trial Compass
RecruitingNot Applicable
Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy
United States40 participantsStarted 2025-06-30
Plain-language summary
This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these tests in TGD individuals, and explore patient-centered options for these tests. By assessing the status of testing and correlation with hysterectomy pathology, this study will provide preliminary data on the current state of guideline-concordant care and provide initial evidence for the development of evidence-based guidelines in the future
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 years and older
* Able to provide voluntary written consent prior to the performance of any research related activity. Patients who can provide informed consent
* Able to understand, speak, read, and write in English
* Patients who have undergone hysterectomy, or plan to have a hysterectomy
* Patients who are transgender and gender diverse"
Exclusion Criteria:
* Opted out of research
* \<18 years old
* Lacks capacity to consent/has diminished capacity to consent
* Cannot provide informed consent
* Those on the study's community advisory board
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Rates of cervical cancer screening and endometrial sampling in TGD individuals
Timeframe: Month 36
2
Whether HPV self-testing affects the rates of cervical cancer screening in TGD individuals