Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients

Inclusion Criteria: * Children of both genders less than 18 years receiving intensive chemotherapy. * Oncology patients receiving intensified chemotherapy at Oncology unit, Children's Hospital, Ain Shams University, Egypt, who meet the following criteria: * Taking intensified chemotherapy * A healthy oral mucosa. Exclusion Criteria: * Allergy to bee products. * Severe systemic illness unrelated to cancer (Diabetes, Hypertension, …) * Inability to take oral medication or unwillingness to participate in the study * Radiotherapy in the head and neck area. * Malignant or potentially malignant lesions of the oral cavity. * Undergoing any other procedures to prevent oral mucositis except standard oral care. * Patients are unable to commit to the study.