Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients (NCT07073092) | Clinical Trial Compass
Not Yet RecruitingPhase 2
Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients
Egypt50 participantsStarted 2025-07-15
Plain-language summary
The goal of this clinical trial is to evaluate the efficacy of propolis in the prevention of oral mucositis and reducing pain score in children undergoing chemotherapy, and assessing its impact on body mass index, pediatric quality of life and total antioxidant assay. The main question it aims to answer is:
What is the effect of propolis on oral mucositis scores in children undergoing chemotherapy?
Participants will:
Take propolis 3 times daily for 21 days follow up weekly for 3 weeks
Who can participate
Age range
2 Years – 18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children of both genders less than 18 years receiving intensive chemotherapy.
* Oncology patients receiving intensified chemotherapy at Oncology unit, Children's Hospital, Ain Shams University, Egypt, who meet the following criteria:
* Taking intensified chemotherapy
* A healthy oral mucosa.
Exclusion Criteria:
* Allergy to bee products.
* Severe systemic illness unrelated to cancer (Diabetes, Hypertension, …)
* Inability to take oral medication or unwillingness to participate in the study
* Radiotherapy in the head and neck area.
* Malignant or potentially malignant lesions of the oral cavity.
* Undergoing any other procedures to prevent oral mucositis except standard oral care.
* Patients are unable to commit to the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.