CompletedNot Applicable

Evaluation of the Effect of Different Biomaterials on Palatal Wound Healing.

Egypt40 participantsStarted 2025-03-20

Plain-language summary

All study subjects will sign written informal consent form before enrolment. They will be divided into four groups, 10 patients each: * Group I: Palatal wound will be left to heal spontaneously, * Group II: Palatal wound will be covered with Composite stent, * Group III: Palatal wound will be covered with PRF, * Group IV: Palatal wound will be covered with Ora-aid patch. III- Surgical Procedures: - * After harvesting the palatal soft tissue graft with the standardized dimensions (12 × 7 mm) of the graft for all patients. Graft thickness was standardized as well to be approximately 1.5 to 2 mm and confirmed with a caliper at 3 points (ends and centre of the graft). Fixing of the graft at the recipient site will be performed, back to the donor site for management, the blood clot will be wiped with gauze, then placement of different materials according to each group. * The dressing will be then pressed gently for 10 seconds, to aid its adherence to the wound. Fixation of the patch will be followed, using 5/0 propylene suture, with performing sling horizontal figure eight suture technique.

Who can participate

Age range

20 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria:- * Patients who are indicated for soft tissue augmentation procedures, either with root coverage or to increase the deficient keratinized tissue, * Medically free patients, * Non-smokers and * Patients with good oral hygiene. Exclusion Criteria:- * Pregnant or lactating females, * Patients with untreated periodontal condition and * Patients with uncontrolled systemic condition.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Wound healing assessment

Timeframe: From enrollment to the end of treatment at 4 weeks

Pain using the visual analogue scale

Timeframe: From enrollment to the end of treatment at 4 weeks

Trial details

NCT IDNCT07072182

SponsorFatma saad saad mahmoud elsherbini

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-20

View on ClinicalTrials.gov More Heal Wound trials