RecruitingNot Applicable

Sonic vs Passive Ultrasonic Irrigation for Chronic Apical Periodontitis

China300 participantsStarted 2024-12-30

Plain-language summary

This randomized, controlled, double-blinded clinical trial aims to directly compare the efficacy of Sonically Activated Irrigation (SAI) versus Passive Ultrasonic Irrigation (PUI) in the root canal treatment of teeth with chronic apical periodontitis, analyze potential influencing factors, and thereby identify a highly effective and safe root canal irrigation protocol. The ultimate goal is to provide an evidence-based rationale for optimizing irrigation technique selection and overall treatment strategies for chronic apical periodontitis.

Who can participate

Age range18 Years – 59 Years

SexALL

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Inclusion criteria

✓. Agree to participate in this study and provide informed consent;
✓. Age 18-59 years at the time of enrolment;
✓. At least one permanent tooth diagnosed with chronic periapical periodontitis at root development stage of Nolla10th;
✓. Able to follow up on schedule.

Exclusion criteria

✕. Allergies to any medications or materials necessary to complete the procedures;
✕. Non-restorable teeth, teeth with severe defects, or teeth that need to be extracted due to orthodontic treatment;
✕. Teeth with root canal treatment or vital pulp therapy;
✕. Teeth with canal calcification or root canal instrument separation;
✕. Teeth with root fracture or vertical root fracture;
✕. Tooth with internal or external root resorption;
✕. Patients with periodontitis;
✕. Patients with orthodontic treatment;

What they're measuring

Therapeutic Effect Evaluation

Timeframe: 12 months after treatment

Trial details

NCT IDNCT07069881

SponsorNanfang Hospital, Southern Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

Contact for this trial

Liang Yuee

0086-020-62787149 yueeliang734@sina.com

View on ClinicalTrials.gov More Chronic Apical Periodontitis trials