Greater Occipital Nerve Block Alone Versus Dual Nerve Block in Cervicogenic Headache and Occipita… (NCT07068451) | Clinical Trial Compass
CompletedNot Applicable
Greater Occipital Nerve Block Alone Versus Dual Nerve Block in Cervicogenic Headache and Occipital Neuralgia
Syria160 participantsStarted 2020-01-01
Plain-language summary
This study looked at two types of nerve block injections used to treat people with cervicogenic headache (CEH) and occipital neuralgia (ON)-two painful conditions that often cause pain at the back of the head and neck. The injections target nerves in the upper neck that may be causing the pain.
The researchers compared:
One nerve injection (greater occipital nerve block, or GONB), versus
Two nerve injections (GONB plus lesser occipital nerve block, or LONB).
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Adults aged 18 to 65 years
Clinical diagnosis of cervicogenic headache (CEH) and/or occipital neuralgia (ON) according to ICHD-3 criteria
Pain duration of more than 3 months
Pain localized to the occipital region, consistent with the distribution of the greater and/or lesser occipital nerves
Inadequate response to conservative therapy (e.g., analgesics, physiotherapy)
Willingness to participate and provide written informed consent
Exclusion Criteria:
Previous nerve block or other interventional procedures for headache
Use of systemic corticosteroids within the past 3 months
Known allergy to lidocaine or other amide-type local anesthetics
Evidence of secondary causes of headache on imaging (e.g., tumor, infection)
Pregnancy or breastfeeding
Active infection at the injection site
Coagulopathy or use of anticoagulant therapy
Significant psychiatric or neurological comorbidities interfering with study participation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in pain intensity measured by the Visual Analog Scale (VAS)
Timeframe: Baseline, 24 hours, 3 weeks, and 3 months post-intervention