The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Eld… (NCT07066111) | Clinical Trial Compass
Not Yet RecruitingPhase 4
The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Elderly Patients Undergoing Hip Fracture Surgery
China40 participantsStarted 2025-07-20
Plain-language summary
To explore the effects of bupivacaine liposomes in preemptive analgesia for iliofascial block on postoperative pain and postoperative delirium in elderly patients with hip fractures, to optimize perioperative analgesia strategies, to reduce the incidence of postoperative delirium, and to improve patient prognosis.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with hip fractures scheduled for surgical treatment (including femoral neck fractures, intertrochanteric fractures, and fractures more than 5 cm below the lesser trochanter of the femur).
* Age ≥65 years.
* American Society of Anesthesiologists (ASA) grade I - III.
* The patient or family member signed the informed consent form
Exclusion Criteria:
* Compound injuries (such as combined fractures of the head, chest, pelvis, or limbs).
* Have a clear history of mental illness or are taking psychotropic drugs.
* Preoperative delirium or the use of delirium-related medications (such as olanzapine).
* A history of acute cerebrovascular disease (cerebral infarction or cerebral hemorrhage) within 6 months.
* Patients requiring sedation or postoperative coma due to the condition.
* Allergy to amide local anesthetics.
* Severe arrhythmia or liver or kidney dysfunction
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
POD incidence
Timeframe: Evaluated twice daily within 3 days after surgery (8:00-10:00 and 18:00-20:00)
Trial details
NCT IDNCT07066111
SponsorNanjing First Hospital, Nanjing Medical University