Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physica… (NCT07062315) | Clinical Trial Compass
By InvitationNot Applicable
Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity
China90 participantsStarted 2025-07-31
Plain-language summary
Time-restricted eating (TRE) has gained attention as a promising dietary strategy for enhancing body composition and metabolic health. This innovative eating pattern involves confining daily food intake to a specific window, typically spanning 6-10 hours. Given the lack of consensus on the optimal TRE strategy, this research explores whether tailoring eating windows to individual chronotypes enhances TRE outcomes. This randomized controlled trial aims to evaluate the effects of chronotype-matched versus chronotype-unmatched TRE protocols, compared to a control group, over a 12-week period on visceral fat mass and other metabolic health outcomes in physically inactive adults with central obesity. Additionally, the study seeks to determine whether chronotype-matched TRE offers greater benefits in terms of visceral fat reduction and metabolic improvements compared to chronotype-unmatched TRE. Assessments will be conducted at baseline, and after the 12-week intervention.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Chinese adults, male or female, aged between 18-65 years old;
. BMI of 23 kg/m² or higher, with a waist circumference exceeding 80 cm for females and 90 cm for males;
. Weight stability for at least three months prior to the start of the study;
. Physically inactive, indicated by not meeting established WHO guidelines on physical activity and sedentary behavior (i.e., at least 150-300 minutes of moderate-intensity or at least 75-150 minutes of vigorous-intensity aerobic exercise; or an equivalent combination of moderate and vigorous-intensity activity throughout the week;
. Baseline eating duration exceeding 12 hours per day;
. Identified as either early or late chronotypes (Morningness-Eveningness Questionnaire)
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.