This retrospective observational study aims to investigate the potential role of inflammatory markers associated with Obstructive Sleep Apnoea-Hypopnoea Syndrome (OSAHS) in the pathogenesis of white matter lesions (WML) and asymptomatic lacunar infarction (ALI). The study compares inflammatory marker levels (SAA, TNF-α, IL-6) and the severity of white matter lesions among patients with OSAHS alone, OSAHS with ALI, and a healthy control group to explore the relationship between the severity of OSAHS, inflammation, and cerebrovascular changes.
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Levels of Serum Inflammatory Markers
Timeframe: Measured once at the time of enrollment (on the day of brain MRI scan) during the study period from May 2022 to May 2023
Correlation between Inflammatory Markers and OSAHS Severity
Timeframe: Measured once at the time of enrollment during the study period from May 2022 to May 2023
Correlation between Inflammatory Markers and White Matter Lesion Severity
Timeframe: Measured once at the time of enrollment during the study period from May 2022 to May 2023