Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study

Inclusion Criteria: * • Age: 18-50 years old. * Pattern of melasma: Bilateral symmetrical facial melasma of any pattern. * Fitzpatrick skin phototypes: Types III, IV and V. Exclusion Criteria: * Pregnancy and lactation. * Patients taking oral contraceptive pills, hormonal replacement therapy or treatment for chronic illness at the time of the study or during the past 6 months. * Coexistence of diseases associated with hyperpigmentation such as Addison disease. * History of Scarring and keloid tendency * Active skin infections as active HSV. * Previous history of post- inflammatory hyperpigmentation.