CompletedNot Applicable

Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis

Bangladesh160 participantsStarted 2025-05-27

Plain-language summary

The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral microbial load in participants with plaque-induced chronic moderate or severe gingivitis. Half of the participants will receive guava leaf extract mouth rinse, and the other half will receive Chlorhexidine(CHX).

Who can participate

Age range18 Years – 35 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: • Participants with a minimum of 24 functional teeth. * Presence of Plaque induced chronic moderate to severe form of gingivitis. * Participants within the age group of 18 to 35 years. * Willing and able to comply with all study procedures. Exclusion Criteria: • Pregnant or lactating women. * Systemically compromised people; subjects with removable or fixed orthodontic appliances or prosthesis. * People who were prescribed antibiotics or inflammatory drugs in the past 1 month. * History of smoking or any form of tobacco use. * History of allergic reactions to Chlorhexidine or Guava. * Severe systemic conditions that could contraindicate participation in the study.

What they're measuring

Change in Plaque Index

Timeframe: At baseline, 1 month, and 3 months post-intervention

Change in Gingival Index (GI)

Timeframe: At Baseline, 1 Month, and 3 Months post-intervention

Trial details

NCT IDNCT07059572

SponsorBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-30

View on ClinicalTrials.gov More Chronic Gingivitis, Plaque Induced trials