By InvitationEarly Phase 1

Acute Effects of Powdered Beetroot Extract Supplementation on the Microcirculation of Resistant Hypertensive Individuals

Brazil100 participantsStarted 2024-06-01

Plain-language summary

Arterial hypertension is a major public health issue and is considered to be a new epidemic due to its high mortality and morbidity rates. Elevated blood pressure levels increase the risk of coronary artery disease, heart failure, stroke, chronic kidney disease and death. Dietary nitrate supplementation in the form of beetroot powder extract may offer a more accessible way to increase systemic nitric oxide availability and consequently promote vasodilation in these patients. However, studies are needed to assess its benefits in patients with hypertension.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Resistant hypertensive patients, with a diagnosis documented in medical records, without any change in medication or increase in dosage in the past 30 days. Exclusion Criteria: * Patients will be excluded from the study if they have: neoplasms, heart failure, are using medications containing nitrate in their formulation, or have undergone renal denervation.

What they're measuring

Blood pressure

Timeframe: 60 days of tratment

Trial details

NCT IDNCT07058922

SponsorNational Institute of Cardiology, Laranjeiras, Brazil

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-12

View on ClinicalTrials.gov More Resistant Arterial Hypertension trials