By InvitationNot Applicable

A Study of Carbon 13-based Deep Labelling of Bone Marrow Cells

United States40 participantsStarted 2025-02-01

Plain-language summary

This study evaluates a novel laboratory method to study how certain bone marrow cells in the body take up nutrients from their environment.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All Participants: * At least age 18 years or older * Able to provide informed consent * MGUS Cohort: * International Myeloma Working Group (IMWG) criteria for the diagnosis of non-IgM MGUS Exclusion Criteria: * All Participants: * Unable to provide consent * Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) \>1 * Prior history of adverse events with conscious sedation * Ongoing use of immunosuppressive medications * All known pregnant and lactating women will be excluded

What they're measuring

Extracellular uptake of glucose and amino acids (AAs) between pre-malignant clonal plasma cells (cPCs) and polyclonal plasma cells (pPCs)

Timeframe: Up to 30 days

Trial details

NCT IDNCT07057583

SponsorMayo Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12-31

View on ClinicalTrials.gov More Monoclonal Gammopathy of Undetermined Significance (MGUS) trials