Association Between Qmax/eGFR Ratio and LUTS Severity in Men Over 40 (NCT07055425) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Association Between Qmax/eGFR Ratio and LUTS Severity in Men Over 40
100 participantsStarted 2025-09-01
Plain-language summary
This study will look at how well a measure called the Qmax/eGFR ratio is related to the severity of urination problems in men over the age of 40. Qmax is a test that shows how fast a person can urinate, and eGFR is a number that reflects kidney function. Men who have urinary symptoms will be asked to do a urine flow test, a blood test, and fill out a questionnaire about their symptoms and quality of life. We will study if there is a link between the Qmax/eGFR ratio and how severe their symptoms are. The results may help doctors better understand how kidney and urinary function are related in men with these problems.
Who can participate
Age range
40 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male patients aged 40 years or older presenting with lower urinary tract symptoms (LUTS)
* Able to provide informed consent
* Willing and able to undergo uroflowmetry and blood testing
* Able to complete the IPSS questionnaire, including the QoL item
* Estimated glomerular filtration rate (eGFR) ≥ 30 mL/min/1.73m²
Exclusion Criteria:
* History of urological surgery (e.g., prostatectomy, bladder surgery)
* Diagnosed or suspected prostate cancer
* Active urinary tract infection (based on clinical symptoms or urinalysis)
* Neurological conditions affecting bladder function (e.g., Parkinson's disease, spinal cord injury)
* Presence of an indwelling urinary catheter at enrollment
* eGFR \< 30 mL/min/1.73m²
* Inability to perform uroflowmetry or complete clinical evaluations
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Correlation Between Qmax/eGFR Ratio and Total IPSS Score
Timeframe: At baseline
2
Correlation Between Qmax/eGFR Ratio and IPSS Quality of Life Subscore