Assessment of Serum Catestatin Level in Acne Vulgaris Patients (NCT07054398) | Clinical Trial Compass
RecruitingNot Applicable
Assessment of Serum Catestatin Level in Acne Vulgaris Patients
Egypt60 participantsStarted 2025-01-10
Plain-language summary
Acne vulgaris is a persistent inflammatory condition of the pilosebaceous unit, affecting 85% of people between the ages of 12 and 24, it is regarded as one of the most common diseases in teenagers and young adults.
Catestatin, a peptide derived from chromogranin A (CgA), was first discovered in 1997 as an acute nicotinic-cholinergic antagonist. Later, it was determined that CST is a pleiotropic hormone.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy persons of both sexes with moderate and severe acne.
Exclusion Criteria:
* Pregnant and lactating women.
* Immunocompromised patients.
* Severe anemia.
* History of chronic liver disease.
* Hyperlipidemia
* Non-inflammatory acne conditions.
* History of neurologic disorders.
* History of neoplastic disorders.
* History of cardiac disease.
* History of systemic acne treatment for at least 4 weeks prior to inclusion and no topical treatments for at least 2 weeks.
* Cases with known hypersensitivity reaction to isotretinoin.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Evalaute serum level of Catestatin in acne patient
Timeframe: 12 weeks
2
Evalaute the effect of treatment with systemic isotretinon