CompletedNot Applicable

Efficacy of Nebulized Dexmedetomidine on Blunting Hemodynamic Changes During Intubation and Pneumoperitoneum in Morbid Obese Patients During Laparoscopic Bariatric Surgery

Egypt90 participantsStarted 2025-07-10

Plain-language summary

This study aims to evaluate the effect of preoperative dexmedetomidine nebulization on blunting hemodynamic response for laryngoscope, intubation, pneumoperitoneum, and opioid consumption in morbidly obese patients undergoing laparoscopic bariatric surgery.

Who can participate

Age range20 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age from 20 to 60 years old. * Both sexes. * American Society of Anesthesiologists (ASA) Physical Status I-III. * Morbidly obese patients with a body mass index (BMI) between 30 and 45. Exclusion Criteria: * Patients' refusal * Decompansated hepatic, renal, or cardiac disease * Expected difficult airway management * Uncontrolled hypertension * Psychiatric disease * Sever pulmonary disease * Patients on opioid, alcohol, beta-blockers, or allergy to any of the study drugs.

What they're measuring

Incidence of increase in hemodynamic response

Timeframe: Intraoperatively

Trial details

NCT IDNCT07054138

SponsorTanta University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-30

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