RecruitingNot Applicable

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

United States32 participantsStarted 2025-08-31

Plain-language summary

Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth. This study will test to see if using EMD around implants results in thicker gum tissues around implants.

Who can participate

Age range18 Years – 18 Years

SexALL

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Inclusion criteria

✓. Ability of subject to understand and the willingness to sign a written informed consent document.
✓. Males and females; Age 18 to 89 years old
✓. Require second stage implant uncovering
✓. In either the maxillary or mandibular arch
✓. Has consistent transportation for all clinical and study visits

Exclusion criteria

✕. Pregnancy, or those planning to become pregnant
✕. Allergy or any medical issue using EMD
✕. Non-English speaking
✕. Patients on anticoagulants
✕. Patients who object to the use of animal products

What they're measuring

Mucosal Thickness

Timeframe: One month and 3 months

Change in Keratinized mucosal width

Timeframe: One month and 3 months

Trial details

NCT IDNCT07053969

SponsorThe University of Texas Health Science Center at San Antonio

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-09

Contact for this trial

Angela Palaiologou-Gallis, DDS

210-450-3715 PalaiologouA@uthscsa.edu

View on ClinicalTrials.gov More Dental Implantation trials