RecruitingNot Applicable

Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

United States550 participantsStarted 2025-09-02

Plain-language summary

The investigators hypothesize that pregnancy and preconception care may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal or preconception/fertility care. The goal is to evaluate the acceptability of BRCA1/2 testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention and be cost-effective, especially among underserved populations.

Who can participate

Age range18 Years – 55 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years - 55 years * Pregnant patients receiving obstetrical-related care or receiving preconception/fertility care at a WCM-affiliated enrollment site. * Patients who have elected to undergo OCS with the WCM-affiliated obstetrics provider * Patients with prior OCS but planned to repeat OCS are eligible * Patients can speak and read in English or Spanish Exclusion Criteria: * Patients who have previously completed a multigene hereditary cancer syndrome panel * Patients who have a hematologic cancer or hematologic pre-cancer * Patients who have a history of an autologous bone marrow transplant

What they're measuring

Percentage of Participants Who Complete Both HCS and OCS

Timeframe: Approximately within the end of recruitment expected at 2 years

Trial details

NCT IDNCT07052266

SponsorWeill Medical College of Cornell University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-06

Contact for this trial

Steve Lopez, BA

9143127488 stl4013@med.cornell.edu