CompletedNot Applicable

Background: Isometric Handgrip (IHG) is a Classic Sympatho- Excitatory Stimulus Often Used in Autonomic Testing. Aims: The Aims of This Study Were to Evaluate the Acute Cardiovascular Response and Recovery Following Isometric Handgrip (HG) Exercise-induced Fatigue on Healthy Adults. Secondary, to e

Egypt35 participantsStarted 2024-04-02

Plain-language summary

: Isometric handgrip (IHG) is a classic sympatho- excitatory stimulus often used in autonomic testing. Aims: The aims of this study were to evaluate the acute cardiovascular response and recovery following isometric handgrip (HG) exercise-induced fatigue on healthy adults. Secondary, to examine correlations between isometric handgrip strength and both systolic (SBP) and diastolic (DPB) blood pressure' Methods: Study was a repeated measure single group design. Thirty-five healthy volunteers, 20 females and 15 males, age (36.16 + 6.11years) were enrolled in the study. Study was at out Clinic of October 6 University. Demographic data were collected at beginning of session. Subjects were then assessed for baseline (BL) blood pressure (BP). Maximal isometric voluntary contraction (MIVC) for each subject was the average of two-5 seconds MIVCs of dominant hand using a hand-held dynamometer separated by 1 minute of rest. Subjects were allowed 5 minutes rest, then performed fatigue protocol (FP) using the hand-held dynamometer with their dominant hand at 50% MIVC for 3 minutes as a One minute of rest was given following FP then subjects were reassessed for BP and MIVC of dominant hand respectively (Immediate reassessment). Further, BP was reassessed for 3 times at 5 minutes interval between measures.

Who can participate

Age range

20 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants should fulfil the criteria set for age and BMI ranges. All participants should be medically stable and normotensive. They should not have any physical limitations that prevent performance of IHG exercises. Exclusion Criteria: * Patients will be excluded from the study if they are smokers, under any medications, diabetics, diagnosed with cardiovascular diseases. Also if they have orthopaedic limitations or mental problems that affect the participation and the result of the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

to evaluate the acute cardiovascular response and recovery following isometric handgrip exercise-induced fatigue on healthy adults. and to examine correlations between isometric handgrip strength and both systolic and diastolic blood pressure

Timeframe: from April 2024toMay 2025

Trial details

NCT IDNCT07051837

SponsorOctober 6 University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-04-03

View on ClinicalTrials.gov More Isometric Exercise trials