CompletedNot Applicable

Impact of Protein Content of Milk on Post-Exercise Appetite and Energy Intake

Turkey (Türkiye)16 participantsStarted 2025-05-29

Plain-language summary

This study aims to investigate the acute effects of consuming milk beverages with different protein content on subjective appetite and energy intake in healthy adults following endurance exercise. Participants will complete an endurance exercise protocol and then consume one of three beverages: a high-protein milk, a regular-protein milk, or an isoenergetic and isovolumetric carbohydrate control drink. Subjective appetite ratings will be assessed using visual analogue scales (VAS) at multiple time points after beverage consumption. Appetite-related hormonal responses, including insulin and acylated ghrelin, will be measured via blood samples. Energy intake will be assessed through an ad libitum test meal. This study will help determine whether different types of milk consumed post-exercise influence appetite regulation, hormonal response, and subsequent energy intake.

Who can participate

Age range

18 Years – 39 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The study will include healthy, physically active male participants aged 18-39 years who have been engaging in recreational endurance sports (such as cycling, running, triathlon, orienteering, or team sports) for at least one year, with a minimum frequency of 3 sessions per week lasting 60-90 minutes. Exclusion Criteria: * Current smoker * Chronic or excessive alcohol consumption * Use of supplements and/or chronic medications that may affect appetite * Presence of cardiac, hepatic, renal, pulmonary, neurological, hematological, gastrointestinal, diabetic, thyroid, or psychiatric disorders, and/or musculoskeletal conditions that may limit exercise participation * Allergy or intolerance to any of the foods or beverages to be consumed during the study * Unstable body weight (e.g., weight loss greater than 1 kg in the past week) * Currently following a weight-loss diet * Diagnosed eating disorders or individuals who cognitively restrict food intake (to be assessed using the Three-Factor Eating Questionnaire)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

energy intake

Timeframe: From enrollment to the end of treatment at 3 weeks.

Trial details

NCT IDNCT07050017

SponsorHacettepe University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-29

View on ClinicalTrials.gov More Appetite trials