Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic A… (NCT07049965) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy
India60 participantsStarted 2024-04-01
Plain-language summary
This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.
The ideal method for closing the appendix stump should be safe, reliable, simple to use, and cost-effective. Various techniques have been introduced for this purpose, each with its advantages and disadvantages. However, no clear consensus has been reached in the literature regarding which technique is superior.
This study is to compare the two groups in terms of operative time and postoperative complications and to reach a conclusion as to which one of the two is superior.
Who can participate
Age range
5 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. 5 - 65 years
. Any gender
. Patient willing to undergo laparoscopic appendectomy
. Acute appendicitis confirmed by clinical and radiological analysis
. Alvarado Score ≥7
. Alvarado Score ≥5 with positive ultrasound findings
Exclusion criteria
. Patient with base of appendix highly inflamed / gangrenous
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Operative time
Timeframe: Intraoperative( measured during surgical procedure on day 1)
. Any other intra-abdominal pathology other than acute appendicitis, e.g., appendicular mass, appendicular abscess, tuberculosis, carcinoid tumor, pelvic inflammatory disease, ovarian tumors, ceacal mass, etc.
. Patients declared unfit for laparoscopic surgery during preoperative assessment
. Patients having severe co morbid condition - COPD/CAD/CHF