RecruitingNot Applicable

Gynecological Impact of Allogeneic Hematopoietic Stem Cell Transplantation in Adults

France80 participantsStarted 2025-09-19

Plain-language summary

Gynecological impact and infertility are major issues for women after allogeneic hematopoietic stem cell transplantation. The aim of the present study is to investigate the prevalence of gynecological complications after allogeneic hematopoietic stem cell transplantation for acute leukemia in adulthood. By conducting a single-center retrospective descriptive analysis, the prevalence, follow-up and treatment of gynecological complications -including premature ovarian failure, vulvovaginal graft-versus-host-disease, cervical pathology- will be analysed

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion Criteria: * Women diagnosed with acute leukemia, who underwent allogeneic hematopoietic stem cell transplantation in adulthood (\>18 years), * Aged 20 to 45 at the time of evaluation, * At least 2 years post-transplant. * French-speaking patients, without comprehension disorders, and literate, * No objection to participation. Exclusion Criteria: * Premature ovarian failure prior to management of haemopathy, post-transplant relapse, * Patient under legal protection

What they're measuring

Gynecological complication after transplantation

Timeframe: 2 years

Trial details

NCT IDNCT07048730

SponsorUniversity Hospital, Bordeaux

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07

Contact for this trial

Valerie Bernard, MD, PhD

+33557820940 valerie.bernard@chu-bordeaux.fr

View on ClinicalTrials.gov More Acute Leukemia trials