MRI Evaluation of Graft Maturation Following ACL Reconstruction

Inclusion Criteria: * ACL tear and reconstruction; no other knee ligaments needing reconstruction * Primary (first-time) ACL tear in the affected knee * ACL injury occurred less than 12 months before ACL reconstruction * Have no contraindications or allergies to the treatment administered * Have current imaging studies (plain radiographs and MRI exams within the past 12 months) of the knee to rule out other etiologic diagnoses * Patient underwent ACL reconstruction with a Bone-Patellar Tendon-Bone (BTB) graft harvested from the same knee (ipsilateral autograft) with the Active Matrix tissue * Able and willing to comply with the post-operative study follow-up schedule Exclusion Criteria: * Prior surgery on the index knee within 12 months of enrollment * Steroid injection into the index knee within 6 weeks of enrollment * Chronic ACL tear whereas the injury occurred more than 12 months ago * Multiligamentous injuries whereas any ligament (MCL, PCL, or PLC) in addition to the ACL needs to be reconstructed * Patient underwent ACL reconstruction with a hamstring tendon, Achilles tendon or quadriceps tendon graft (any graft other than a patellar tendon BTB) * Contraindication to MRI (eg, implanted devices incompatible with MRI). * Chrondral lesion of the knee that requires treatment during ACL reconstruction surgery * History of advanced osteoarthritis of the knee or patella-femoral joint; KL grade III or higher * History of malignant tumor and osseous metastatic disease, * Hist…