CompletedNot Applicable

Effects of Pulmonary Resection on Right Ventricular Function

Turkey (Türkiye)33 participantsStarted 2025-04-01

Plain-language summary

Lung resection is associated with high postoperative morbidity and mortality and leads to a significant long-term decrease in functional capacity, particularly due to cardiorespiratory complications. One of the contributing factors to this functional decline is the postoperative reduction in right ventricular function. Due to the anatomical proximity and interactions, right ventricular function is evaluated by echocardiography following lung resection. The pulmonary artery pressure (PAP)/tricuspid annular plane systolic excursion (TAPSE) ratio is a parameter that provides a more comprehensive assessment of right heart function by evaluating both right ventricular systolic function and pulmonary artery pressure. In this study, investigators aimed to evaluate changes in right heart function by performing preoperative and postoperative echocardiographic assessments in participants undergoing lung resection, focusing on PAP/TAPSE ratios.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Adults aged 18 to 80 years ASA classification I-III Patients scheduled to undergo lung resection in thoracic surgery Exclusion Criteria: Patients with arrhythmia Patients using antiarrhythmic drugs Patients with renal failure requiring hemodialysis Patients with a history of previous lung surgery Patients with valvular heart disease Patients with a history of angina pectoris or myocardial infarction within the past month Patients with FEV1/FVC ratio below 60%

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Echocardiographic Assessment: TAPSE/PAP Ratio

Timeframe: 24 hours preoperatively and on postoperative day 2

Echocardiographic Assessment: Tricuspid Annular Plane Systolic Excursion (TAPSE)

Timeframe: 24 hours preoperatively and on postoperative day 2

Echocardiographic Assessment: Pulmonary Artery Pressure (PAP)

Timeframe: 24 hours preoperatively and on postoperative day 2

Trial details

NCT IDNCT07042893

SponsorÇağrı Özdemir

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-04-24

View on ClinicalTrials.gov More Pulmonary Resection trials

Plain-language summary

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Echocardiographic Assessment: TAPSE/PAP Ratio

Timeframe: 24 hours preoperatively and on postoperative day 2

Echocardiographic Assessment: Tricuspid Annular Plane Systolic Excursion (TAPSE)

Timeframe: 24 hours preoperatively and on postoperative day 2

Echocardiographic Assessment: Pulmonary Artery Pressure (PAP)

Timeframe: 24 hours preoperatively and on postoperative day 2