The goal of this study is to learn what the impact of exposure to virtual reality content is on the levels of stress-related blood values in healthy volunteers. The main question it aims to answer is: * To compare the levels of stress-related biomarkers before and after relaxing VR-content (Relax Visit); * To compare the levels of stress-related biomarkers before and after stress-inducing VR-content (Rollercoaster Visit). Researchers will compare the Relax and Rollercoaster Visit to see if there is a relationship between the relaxing and stress-inducing VR content on stress-related blood values. Participants will be asked to watch relaxing or stress-inducing VR content for approximately five minutes. Blood will be withdrawn before and after intervention. After 3-5 weeks the study visit will be repeated using the other VR content.
Age range
18 Years – 45 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
The effect of relaxing VR content on von Willebrand ristocetin co-factor activity
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on von Willebrand ristocetin co-factor activity
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on von Willebrand ristocetin co-factor activity
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)
The effect of relaxing VR content on FVIII activity
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on FVIII activity
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on FVIII activity
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)
The effect of relaxing VR content on copeptin
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on copeptin
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on copeptin
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)
The effect of relaxing VR content on prolactin
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on prolactin
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on prolactin
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)
The effect of relaxing VR content on thyroid stimulating hormone (TSH)
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on TSH
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on TSH
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)
The effect of relaxing VR content on cortisol
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on cortisol
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on cortisol
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)
The effect of relaxing VR content on glucose
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to relaxing VR content (approximately 10 minutes later)
The effect of stress-inducing VR content on glucose
Timeframe: From baseline (5 minutes before start of the VR content during a study visit) to the end of the exposure to stress-inducing VR content (approximately 10 minutes later)
The correlation between relaxing and stress-inducing VR content on glucose
Timeframe: From baseline to the end of the second VR video (type is depending on assigned arm) (approximately 3-5 weeks later)