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Comparing the Efficacy of 75mg Versus 150mg Aspirin for the Prevention of Preeclampsia in High-Risk Pregnant Women

Pakistan340 participantsStarted 2025-11-01

Plain-language summary

This study aims to evaluate the effectiveness of 75 mg aspirin versus 150 mg aspirin in preventing preeclampsia among individuals with high risk for the condition. Existing literature suggests that the 150 mg aspirin dose may exhibit superior efficacy, yet inconclusive evidence exists in our local setting.

Who can participate

Age range18 Years – 30 Years

SexFEMALE

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Inclusion criteria

✓. Screen positive women
✓. Age 18 - 30 y
✓. Gestational Age 11 - 13+6 weeks
✓. Singleton Pregnancy
✓. Estimated risk for preterm PE of \> 1 in 100 (Reference - Fetal Medicine Foundation)

Exclusion criteria

✕. Screen negative women
✕. Age \> 30 y
✕. Gestational Age \> 14 weeks
✕. Multiple Gestation
✕. Estimated risk for preterm PE of \< 1 in 100 (Reference - Fetal Medicine Foundation)

What they're measuring

Pre - eclampsia

Timeframe: 9 months

Trial details

NCT IDNCT07041385

SponsorShalamar Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-06-30

Contact for this trial

Dr. Hafiz Wajahat Naseem Naseem, M.B.B.S

+923237435943 wnaseem60@gmail.com

View on ClinicalTrials.gov More Preeclampsia (PE) trials