RecruitingNot Applicable

Prehospital ECPR in Moravia Silesia Region

Czechia100 participantsStarted 2025-06-17

Plain-language summary

Cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) in specific cases could be improved by Extracorporeal membrane oxygenation (ECMO; ECPR). ECPR could be introduced in hospital after retrieval of an OHCA patient and also faster by implantation on scene. The aim is to verify the effectiveness of ECPR on scene in the Moravian-Silesian region.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * Observed collapse and presumption of cardiac cause of cardiac arrest * Estimated age up to 70 years * Baseline rhythm of ventricular fibrillation or pulseless electrical activity (PEA) * Basic bystander cardiopulmonary resuscitation (CPR), "bystander CPR", telephone assisted CPR (TANR) Exclusion Criteria: * Children or adults with estimated weight below 40 kg * Known major comorbidities of the patient suggesting low rehabilitation potential (e.g. chronic obstructive pulmonary disease (COPD) IV, malignancy in tertiary phase)

What they're measuring

Time from cardiac arrest (collapse) to implantation of ECMO

Timeframe: up to 60 minutes

Hospital mortality

Timeframe: up to 3 weeks

Cerebral Performance Category (CPC) score

Timeframe: 30 days

Neurological outcome (CPC score)

Timeframe: 6 months

Neurological outcome (SF-36)

Timeframe: 6 months

Neurological outcome (EQ-5D)

Timeframe: 6 months

Trial details

NCT IDNCT07041086

SponsorUniversity Hospital Ostrava

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-12-31

Contact for this trial

Jiří Hynčica

0042059737 jiri.hyncica@fno.cz

View on ClinicalTrials.gov More Cardiac Arrest, Out-Of-Hospital trials