Mindfulness to Enhance Cognitive Health in Latino Older Adults (NCT07040904) | Clinical Trial Compass
RecruitingNot Applicable
Mindfulness to Enhance Cognitive Health in Latino Older Adults
United States60 participantsStarted 2024-12-10
Plain-language summary
The primary objective of the proposed research is to investigate the promise and underlying mechanisms of mindfulness training as a preventative lifestyle intervention to enhance cognitive health in Latino older adults, thereby mitigating risk of Alzheimer's Disease (AD) in a population that may be particularly vulnerable.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Hispanic/Latino
* Age 65 and older
* Male, female, or non-binary
* Community living
* Medically stable and willing to undergo the study procedures
* No extensive mindfulness training experience
Exclusion Criteria:
* Clinically unstable psychiatric disorder that requires immediate treatment (e.g., ECT)
* Medical conditions suggesting significantly shortened lifespan (e.g., metastatic cancer) or prohibiting safe participation in the interventions/assessments (e.g., Parkinson's disease, musculoskeletal conditions)
* Sensory impairment (hearing, vision) preventing participation
* Current alcohol or substance abuse
* Current/concurrent cognitive training known to affect neuroplasticity (e.g., brain-training programs), or other interventions expected to affect neuroplasticity significantly (e.g., psychedelics, cholinesterase inhibitors, high-dose sedatives).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is specifically for Latino older adults — can you help me understand whether my background, age, and current cognitive health make this worth exploring with the research team?
2The study is measuring brain activity with EEG and doing behavioral tasks like reaction time tests — what does that kind of participation actually involve in terms of time, visits, and what they'd be asking me or my family member to do?
3Since this is a mindfulness-based study rather than a drug trial, what do we currently know about whether mindfulness programs can realistically slow or reduce the risk of Alzheimer's-related dementia in older adults?
4The trial is measuring several different outcomes — brain markers, attention scores, emotional wellbeing — does that suggest this is still in an early stage of figuring out whether mindfulness works, and how does that affect what we might gain by participating versus just pursuing standard care or support programs?
5Are there existing community-based programs or standard cognitive health resources available to Latino older adults that I should consider alongside or instead of joining this research study?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
EEG brain markers of cognitive functioning
Timeframe: Time-frame: 2 time-points - baseline/pre-intervention, and immediately after the intervention
2
EEG brain markers of cognitive functioning
Timeframe: Time-frame: 2 time-points - baseline/pre-intervention, and immediately after the intervention
3
AXCPT behavioral performance (reaction time)
Timeframe: Assessed at 2 timepoints: baseline/pre-intervention immediately post-intervention
4
AXCPT behavioral performance score (accuracy)
Timeframe: Assessed at 2 timepoints: baseline/pre-intervention immediately post-intervention
5
Five Facet Mindfulness Questionnaire (FFMQ) score
Timeframe: Performed during the intervention (3x /week for 8 weeks)
6
The Mindful Attention Awareness Scale (MAAS) score
Timeframe: Performed during the intervention (3x /week for 8 weeks)
7
Cognitive and Affective Mindfulness Scale (CAMS-R) score