Not Yet RecruitingNot Applicable

EVALUATION OF NEUTROPHIL FLUORESCENCE IN PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION ASSOCIATED WITH SEPTIC SHOCK

France100 participantsStarted 2025-07-01

Plain-language summary

Neutrophil fluorescence could be a reliable and early diagnostic marker of disseminated intravascular coagulation septic DIC, which can be used routinely. The objective of the investigators is to define the optimal threshold of neutrophil fluorescence associated with a sensitivity of at least 90% for the diagnosis of DIC.

Who can participate

Age range18 Years

SexALL

See this in plain English?

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Inclusion Criteria: * Male or female ≥ 18 years of age * Patient admitted to intensive care for septic shock * Patient affiliated to a social security scheme or entitled to it * Non-opposition by the patient or a relative in the event that the patient is not in a state to express his or her consent or inclusion in an emergency procedure in the event that the patient is not in a state to express his or her opinion and no relative of the patient can be reached. Exclusion Criteria: * Dying patient on the day of inclusion * Cirrhosis Child Pugh C * Neutropenia (\<500 mm3) * Patient under judicial protection * Patient under guardianship or curatorship * Pregnancy * Breastfeeding

What they're measuring

Define the optimal threshold for neutrophil fluorescence (measured at admission of the patient to intensive care on a new automaton) associated with a sensitivity of at least 90% for the diagnosis of disseminated intravascular coagulation DIC.

Timeframe: 1 month

Trial details

NCT IDNCT07039487

SponsorUniversity Hospital, Strasbourg, France

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-07-01

Contact for this trial

Ferhat MEZIANI, Professor

+33369551021 ferhat.meziani@chru-strasbourg.fr