By InvitationNot Applicable

Clinical Alternatives for Reducing Harm Using E-cigarettes

United States208 participantsStarted 2025-08-25

Plain-language summary

For patients in cancer care, quitting smoking is critical, but a significant portion of patients in cancer care refuse all components of tobacco treatment, even when offered free of charge. The proposed clinical trial will assess one harm reduction intervention, switching completely from cigarettes to e-cigarettes, among oncology outpatients who smoke and refuse traditional tobacco treatment. This study is a type 1 hybrid effectiveness-implementation trial among oncology outpatients at an NCI-designated cancer center who smoke and refuse all components of tobacco treatment (N=208).

Who can participate

Age range21 Years

SexALL

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Inclusion Criteria: * age 21+, * identified as smoking in their medical record and self-report of current smoking within the past 30 days * refused traditional treatment options through the opt-out HCC Tobacco Treatment Program * English speaking; Exclusion Criteria: * currently taking part in any TTP or using cessation medication (i.e., taking NRT or other cessation medications, enrolled in the Quitline, or in another study), * use of e-cigarettes in the past 30 days, * currently imprisoned, * pregnant women.

What they're measuring

Complete switching

Timeframe: 6 months

Trial details

NCT IDNCT07039292

SponsorMedical University of South Carolina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-05-31

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