β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972. Research has shown non-asthmatics receive no benefit from these drugs at therapeutic dosages; however, many elite athletes still use them, and asthmatic athletes often win more Olympic medals. In some non-asthmatics, β2-agonists may improve breathing limitations during high intensity exercise, which may improve performance. Therefore, we aim to examine if there is a select group of non-asthmatic individuals who experience breathing limitations that may receive benefit from β2-agonists.
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Difference in time to exhaustion following salbutamol inhalation compared to placebo inhalation.
Timeframe: Up to 2 weeks
Sex differences in time to exhaustion following salbutamol inhalation
Timeframe: Up to 2 weeks