The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltrati… (NCT07035314) | Clinical Trial Compass
RecruitingNot Applicable
The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
Egypt75 participantsStarted 2025-03-08
Plain-language summary
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
Who can participate
Age range4 Years – 10 Years
SexALL
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Inclusion Criteria:
* Age: Between 4-10 years.
* Indications of tonsillectomy such as:
* Recurrent acute attacks at least 7 episodes in the past year or at least 5 episodes per year for 2 years or at least 3 episodes per year for 3 years.
* Chronic tonsillitis and hypertrophy of tonsils causing sleep apnea, difficulty in deglutition, interference in speech.
* Tonsillectomy by cold dissection only.
* American Society of Anesthesiologists (ASA) classification 1,2 (Normal Health, Mild systematic disease).
Exclusion Criteria:
* Patients with age less than 4 and more than 10 years.
* Indications of tonsillectomy other than chronic tonsillitis such as lymphoma.
* Patients on chronic steroid therapy
* Hemoglobin level less than 10 gm/dL
* Presence of acute infection in the upper respiratory tract, acute tonsillitis
* American Society of Anesthesiologists (ASA) classification ASA 3,4 (Severe systematic disease such as uncontrolled Diabetes, cardiac disease, liver or kidney disease, life threating medical conditions)
* Regular use of analgesics within a week of surgery.
What they're measuring
1
post tonsillectomy pain
Timeframe: DAY 0 6h, 24h post-operatively and DAY 5 post-operatively