RecruitingNot Applicable

The Relationship Between Preoperative Frailty and Postoperative AKI and the Mediating Effect of Intraoperative BP

China1,000 participantsStarted 2025-07-01

Plain-language summary

The primary objectives of study is to compare the difference in the incidence of postoperative AKI between frail and non-frail patients. The secondary objectives of study was to compare the differences in intraoperative blood pressure fluctuations, the incidence and duration of intraoperative hypotension, postoperative extubation time, postoperative complications, length of hospital stay and hospitalization expenses between frail and non-frail patients, and use mediating effect analysis to examine the magnitude of the effect of intraoperative blood pressure on postoperative acute kidney injury caused by frailty.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years old or above * Undergo non-cardiac surgery Exclusion Criteria: * At least one measurement of serum creatinine (SCr) was not conducted before and after the operation * End-stage renal disease (ESRD) that has received dialysis within the past year * Baseline SCr ≥ 4.5 mg/dl (because the clinical criteria for AKI based on elevated SCr may not be applicable to these patients) * Acute kidney injury occurred within 7 days before the operation * No frailty assessment was conducted * The surgical procedure is renal surgery * The operation time is less than 2 hours

What they're measuring

Postoperative acute kidney injury

Timeframe: Within one week after the operation

Trial details

NCT IDNCT07030179

SponsorLanyue Zhu

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-31

Contact for this trial

Yue Lan Zhu

+8618795969178 zhulanyue1993@126.com

View on ClinicalTrials.gov More Postoperative Acute Kidney Injury trials