This observational cohort study will investigate the association between oxidative stress biomarkers and post-COVID-19 cognitive impairment. A total of 45 recovered COVID-19 patients aged 30-65 will be enrolled and followed at three intervals: 0-3, 3-6, and 6-12 months post-infection. Cognitive function will be assessed using standardized memory and attention tests, while venous blood samples will be analyzed for nitric oxide, AOPP, NETs, and extracellular nucleic acids. The study aims to identify early predictors of long COVID cognitive sequelae and evaluate biological mechanisms underlying persistent neurocognitive symptoms.
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Change in Wechsler Memory Scale (WMS) Scores
Timeframe: Measured at 0-3, 3-6, and 6-12 months after discharge.
Change in Bourdon Attention Test Scores
Timeframe: Measured at 0-3, 3-6, and 6-12 months after discharge.