High Intensity Resistance Training + Creatine in Perimenopause

Inclusion Criteria: * Women transitioning through perimenopause (defined by the North American Menopause Society Menopause Health Questionnaire), with or without hormone therapy or experiencing two or more perimenopause-related symptoms, as determined from the validated North American Menopause Society * Women ≥38-60 yrs. * Recreationally active \[(≥30 minutes of moderate-intensity physical activity per week and \<3 times per week of progressive resistance training, as defined by the International Physical Activity Questionnaire (IPAQ)\] * Body mass index of 18.5-34.9 kg/m\^2 * Is at risk or has a current chronic disease that is not contraindicated by exercise, and could be improved by resistance exercise (i.e. type 2 diabetes, heart disease, hypertension, hypercholesterolemia, hyperthyroidism, depression, osteoporosis, etc.) Exclusion Criteria: * Experienced a musculoskeletal injury within the past three months that inhibits participation in the study. * Has chronic kidney disease, liver disease, chronic obstructive pulmonary disease, or cancer * Currently using medications that may directly impact the primary outcomes including: diuretics and corticosteroids). * Currently using creatine monohydrate or other performance-enhancing supplements * Has a self-identified or clinically diagnosed eating disorder * Currently pregnant or planning to become pregnant (determined from urine pregnancy test) * Currently nursing or have had a child within the previous 6 months * Has part…