This study will investigate the efficacy of a mushroom blend to improve gastrointestinal symptoms and mood. It will also be determining if the mushroom blend has an effect on the gut microbiome and metabolomics.
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Changes in the gastrointestinal symptoms rating scale.
Timeframe: Visit 2 (Day 0), Visit 3 (Day 19-21), Visit 4 (Day 42)
Changes in Assessment of Constipation - Quality of Life
Timeframe: Visit 2 (Day 0), Visit 3 (Day 19-21), Visit 4 (Day 42)
Changes in total mood disturbances
Timeframe: Visit 2 (Day 0), Visit 3 (Day 19-21), Visit 4 (Day 42)
Changes in the gastrointestinal microbiota alpha diversity
Timeframe: Visit 2 (Day 0) and Visit 4 (Day 42)
Changes in the gastrointestinal microbiota beta diversity
Timeframe: Visit 2 (Day 0) and Visit 4 (Day 42)
Changes in the gastrointestinal microbiota relative abundance of specific gut bacteria based on amplicon sequence variants.
Timeframe: Visit 2 (Day 0) and Visit 4 (Day 42)
Changes in water-soluble polar metabolites.
Timeframe: Visit 2 (Day 0) and Visit 4 (Day 42)