CompletedNot Applicable

Comparison of LSTR and Pulpectomy in Primary Molars of Pediatric Patients (LSTR-PULP)

Turkey (Türkiye)110 participantsStarted 2024-08-16

Plain-language summary

This study aims to compare the effectiveness of Lesion Sterilization and Tissue Repair (LSTR) with conventional pulpectomy in treating pulpal lesions in primary molars of pediatric patients aged 4 to 10 years. LSTR is a minimally invasive method that uses antibiotic paste to disinfect infected tissue without full canal instrumentation. Children participating in this study will receive either the LSTR technique or standard pulpectomy, and the clinical and radiographic success of both treatments will be evaluated over a 12-month period. The goal is to determine whether LSTR is a safe and effective alternative to pulpectomy in primary teeth.

Who can participate

Age range

4 Years – 10 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children aged 4 to 10 years. * Presence of at least one primary molar with pulpal involvement requiring endodontic treatment. * Good general health without systemic conditions. * Signed informed consent from parent or legal guardian. Exclusion Criteria: * Children with systemic diseases or immune-compromising conditions. * Known allergies to any of the materials or antibiotics used in the study. * Uncooperative behavior preventing dental treatment under normal clinical conditions. * Teeth with non-restorable crown structure or excessive root resorption.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical Success Rate of Treated Primary Molars

Timeframe: At 3, 6, and 12 months post-treatment

Trial details

NCT IDNCT07026435

Sponsortaymour abuawwad

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09-14

View on ClinicalTrials.gov More Pulpal Necrosis trials