Xenogenic Collagen Matrix vs. Connective Tissue Graft for Soft Tissue Augmentation Around Early M… (NCT07024186) | Clinical Trial Compass
CompletedNot Applicable
Xenogenic Collagen Matrix vs. Connective Tissue Graft for Soft Tissue Augmentation Around Early Maxillary Implants
Egypt20 participantsStarted 2022-03-17
Plain-language summary
This study compares two methods used to improve gingival tissue around dental implants placed in (the maxillary esthetic zone). After a tooth is removed and a dental implant is placed early (usually 4-8 weeks later), additional soft tissue is sometimes needed to ensure the implant looks natural and functions well. The two techniques being studied are:
Subepithelial connective tissue graft (SCTG) - where tissue is taken from the patient's own mouth (usually the palate)
Xenogeneic collagen matrix (XCM) - a processed collagen material from animals, used as a substitute for the patient's own tissue.
The goal is to see which method is better in terms of gingival thickness, esthetic appearance, healing, and patient comfort. This research may help dentists choose the most effective and comfortable treatment for their patients.
Who can participate
Age range
25 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
\*\*Inclusion Criteria:\*\*
* Non-restorable or hopeless teeth from maxillary anterior to first premolar due to one or more of the following:
* Extensive caries
* Root fractures
* Inability to perform functional crown lengthening due to gingival zenith line with high gingival display
* Improper crown-to-root ratio due to bone removal leading to aesthetic or restorative failure
* Patients aged 25-55 years
* Both male and female patients
* Thin tissue biotype
\*\*Exclusion Criteria:\*\*
* Pregnant women
* Smokers
* Presence of persistent chronic infection at the implant site
* Patients in the growth phase with partially erupted teeth
* Patients with parafunctional habits such as bruxism or clenching that may overload the implant
* Patients with insufficient vertical inter-arch space in centric occlusion to accommodate restorative components
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.