Short-term and Intermediate-term Effects of Self-applied Joint Mobilization Versus Clinician-appl… (NCT07020897) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Short-term and Intermediate-term Effects of Self-applied Joint Mobilization Versus Clinician-applied Joint Mobilization in Addition to Exercise in Patients With Knee Osteoarthritis: A Randomized Clinical Trial
United States24 participantsStarted 2025-07-15
Plain-language summary
The goal of this clinical trial is to learn if a combination of patient self-administered joint mobilization and exercise works to treat knee osteoarthritis in adults. The main questions it aims to answer are:
* Does self-administered joint mobilization improve the ability to perform regular daily activities?
* Does self-administered joint mobilization improve knee motion?
* Does self-administered joint mobilization improve hip strength?
Researchers will compare the program of self-administered joint mobilization to a joint mobilization administered by a physical therapist.
Participants will:
* Attend 8-12 physical therapy clinic visits over 6 - 8 weeks
* Perform home exercises
* Visit the clinic 6 months later for a brief check-up
Who can participate
Age range
45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Meets National Institute for Health and care Excellence (NICE) criteria for knee osteoarthritis:
* Age 45 years or older
* Movement-related knee pain
* No morning stiffness or morning stiffness \< 30 minutes
* Knee flexion contracture (kFC) at least 1cm, measured by heel-height
* Fluency in verbal and written English for completion of outcome measure and screening, and to take directions.
* Able to attend all study-related appointments
Exclusion Criteria:
* Assistive device required for ambulation
* Systemic disease affecting joint function (diabetes, rheumatological disorders, etc)
* Previous lower extremity joint replacement
* Lower quarter surgery, injection, or therapy in the past year
* Other functionally-limiting physical impairment of the lower quarter
* Spine or lower extremity compensation claim (work, accident, etc)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Western Ontario and McMaster Universities Arthritis Index (WOMAC)