Active — Not RecruitingNot Applicable

Effect of Electrical Diaphragmatic Stimulation on Chronic Obstructive Pulmonary Disease

Egypt120 participantsStarted 2024-08-01

Plain-language summary

Respiratory muscle dysfunction is a common consequence of chronic obstructive pulmonary disease (COPD). This technique consists of placing electrodes on the skin at locations near the motor points of the diaphragm, transmitting an intermittent current, and generating action potentials capable of producing muscle contractions

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>18 years. * Known cases of COPD admitted at respiratory critical care unit with severe acute exacerbation (defined according to GOLD 2024). Exclusion Criteria: * Body mass index (BMI) \> 35 kg/m2 * Post arrest patients * Brain death * Hemodynamic instability * Invasive MV * Lung disease other than COPD * Pregnancy , ascitis. * History of neuromuscular disease at admission * Spinal injuries * Skin lesions or an open lesion in the regions where the electrodes would be placed * Use of pacemakers * Patients on maintenance steroid therapy * Depletating disease as malignancy 14. Patients refusing the procedure

What they're measuring

The primary outcome is the progression to invasive mechanical ventilation(IMV)

Timeframe: 6 months

Trial details

NCT IDNCT07020299

SponsorMansoura University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-01

View on ClinicalTrials.gov More Diaphragm Electrical Activity trials