Not Yet RecruitingNot Applicable

A Study of Body Fat Distribution and Airway Mechanics in Healthy Adults

20 participantsStarted 2028-01-01

Plain-language summary

This study investigates how body fat distribution affects airway closure and lung mechanics in healthy adults. Using Electrical Impedance Tomography (EIT), esophageal manometry, and computed tomography (CT), we aim to characterize how varying BMI and fat topography influence regional ventilation and airway collapse in supine and prone positions. Healthy volunteers with a range of BMIs will undergo a 2-hour imaging session with noninvasive and minimally invasive monitoring.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion Criteria • Healthy subjects older than 18 years and younger than 80. Exclusion Criteria * Pre-existing cardiopulmonary disease * history of tobacco or ecigarette smoking

What they're measuring

Lung volumes

Timeframe: Day 1, 15 minutes after breathing in the supine and in the prone position

Trial details

NCT IDNCT07019831

SponsorMaurizio F. Cereda, MD

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-12-31

Contact for this trial

Maurizio Cereda, MD

16176430987 mcereda@mgh.harvard.edu

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