Gender-affirming Voice Training With Visual Feedback (NCT07017595) | Clinical Trial Compass
TerminatedNot Applicable
Gender-affirming Voice Training With Visual Feedback
Stopped: Funding was terminated by NIH in 2025 with a statement that the research no longer meets agency priorities.
United States6 participantsStarted 2025-06-05
Plain-language summary
The goal of this clinical trial is to learn if prototype software can be used to train vocal pitch and resonance in trans women. The main questions it aims to answer are:
* How regularly would trans women use the prototype voice training software as "homework" between human-led voice training sessions?
* In such a setting, how usable and motivating would the training software be?
Participants will first have their voice measured, then take part in four virtual sessions (one per week) led by a speech-language pathologist. In each session, the clinician will guide the participant through several voice exercises both with and without the software. Participants will be asked to use the software to exercise on their own for about 2x 15 minutes a day between virtual sessions.
Who can participate
Age range
18 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* At least 18 years old.
* Native speaker of American English - must have been exposed to it by the age of 6.
* Assigned male at birth, currently identifies as transgender.
* Currently interested in gender-affirming voice training.
* Has access to a computer and quiet room for performing voice training.
* Able to pass a pure-tone hearing screening at 20dB HL.
Exclusion Criteria:
* Current or previous diagnosed speech, language or hearing problems (besides voice-gender dysphoria).
* Neurological disorder or disease (e.g., Parkinson's, tremor) or impacted nerve function to the larynx (e.g., paralysis/paresis of the vocal fold).
* Respiratory disease (e.g., asthma).
* Nasopharyngeal pathology or anatomical abnormality.
* Previous voice feminization surgery.
* Engaged in other gender-affirming voice training during period of study participation.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Intrinsic Motivation Inventory (IM)
Timeframe: During the first and fourth intervention sessions
2
Time on task
Timeframe: Data collected throughout the three-week duration of training