CompletedNot Applicable

Post-Implantation Syndrome and Laboratory Markers Following EVAR and TEVAR

Turkey (Türkiye)300 participantsStarted 2018-01-01

Plain-language summary

The aim of this observational study is to investigate the relationship between postimplantation syndrome (PIS) and laboratory inflammatory parameters following endovascular aortic repair (EVAR/TEVAR). PIS is a systemic inflammatory response that may occur after EVAR or TEVAR and lacks a standardized clinical definition. This study seeks to determine whether specific laboratory biomarkers-particularly white blood cell count, C-reactive protein (CRP), interleukin levels, and neutrophil-to-lymphocyte ratio (NLR)-can serve as reliable indicators for the diagnosis and assessment of PIS.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Patients aged ≥18 years * Undergoing elective EVAR or TEVAR for abdominal or thoracic aortic aneurysm * Ability to provide informed consent * Availability of baseline and follow-up laboratory data (including IL-6, NLR, CRP, leukocyte count, procalcitonin, etc.) Exclusion Criteria * Evidence of active infection at the time of procedure * Known autoimmune or inflammatory disease (e.g., rheumatoid arthritis, lupus) * Current use of immunosuppressive or anti-inflammatory therapy * Malignancy under active treatment * End-stage renal or hepatic failure * Emergency or ruptured aneurysm repair * Incomplete postoperative laboratory data

What they're measuring

Evaluation of Postimplantation Syndrome (PIS) Incidence

Timeframe: 0-8 days

Trial details

NCT IDNCT07014839

SponsorAtaturk University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-31

View on ClinicalTrials.gov More Postimplantation Syndrome trials