RecruitingNot Applicable

Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD

United States40 participantsStarted 2025-09-02

Plain-language summary

Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of ESKD diagnosis and receiving hemodialysis for at least 3 months * Can read and speak English * Fatigue measured via visual analogue scale, score ≥4 over the last week * Able to stand and walk one block * Has a cell phone that can receive text messages Exclusion Criteria: * Patient's nephrologist refuses for them to participate * Unstable angina * Unstable pulmonary disease or pulmonary symptoms that preclude participation * Lower-extremity amputation without prosthetic (BKA, AKA) -Orthopedic or neurologic condition that would preclude walking or tensing/releasing of muscles- * Cognitive impairment that, in the judgement of the research team, precludes trial participation * Participation in the formative phase of the development of Fight Fatigue

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Since this trial is studying whether the program is even feasible and acceptable to patients — rather than proving it works — what does that mean for what I might actually get out of participating compared to just continuing my current dialysis routine?
2The trial combines progressive muscle relaxation with a walking program specifically for dialysis patients with fatigue — given my current energy levels and physical condition, is something like this realistic for me to commit to regularly?
3Since the researchers are measuring how well people stick to the protocol, does that mean the schedule of exercises and walks is fairly demanding, and how much time and effort should I expect this to add to my week on top of dialysis sessions?
4Are there any risks specific to starting a new walking or muscle relaxation program while I'm on dialysis that I should be aware of before discussing whether to join this study?
5Would my doctor recommend I try any standard approaches for dialysis-related fatigue first, or does this trial represent something that isn't otherwise available to me right now?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Feasibility of recruitment

Timeframe: Baseline to week 12

Feasibility of retention

Timeframe: Baseline to week 12

Acceptability

Timeframe: End of study (Week 12)

Adherence to the study protocol

Timeframe: Baseline to week 12

Trial details

NCT IDNCT07014111

SponsorUniversity of Illinois at Chicago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-02

Contact for this trial

Mary Hannan, PhD

3123554838 mhanna22@uic.edu

View on ClinicalTrials.gov More End Stage Renal Disease on Dialysis trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.