Active — Not RecruitingNot Applicable

Efficacy of Laser Therapy for Periodontitis

Yemen21 participantsStarted 2025-07-01

Plain-language summary

The aim of this study is to evaluate the efficacy of diode laser in addition to periodontal treatment in periodontitis patients and to investigate their effects on gingival crevicular fluid (GCF) cytokine levels before and after treatment, among some Yemeni individuals in Sana'a city.

Who can participate

Age range25 Years – 58 Years

SexALL

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Inclusion criteria

✓. Patients diagnosed with generalized periodontitis (presence of bleeding on probing \[BOP\] and probing pocket depth \[PPD\] ≥ 4 mm)
✓. Age between 25 and 58 years
✓. Presence of at least 20 natural teeth present.

Exclusion criteria

✕. Smokers or qat chewers
✕. Pregnant or lactating women
✕. Patients taking medications that may influence periodontal tissue status
✕. Patients with systemic conditions affecting periodontal health
✕. Patients who received periodontal therapy or antibiotic treatment within the last 3 months
✕. Patients wearing intraoral appliances or having dental prostheses

What they're measuring

Plaque Index (PI)

Timeframe: Baseline,1 month, 3months after treatment

Gingival Index( GI)

Timeframe: Baseline,1 month, 3months after treatment

Periodontal Pocket Depth (PPD)

Timeframe: Baseline,1 month, 3months after treatment

Clinical attachment level (CAL)

Timeframe: Baseline,1 month, 3months after treatment

Trial details

NCT IDNCT07013162

SponsorUniversity of Science and Technology, Yemen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-01

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