Relationship Between Remimazolam and Etomidate in Induction of General Anesthesia (NCT07012902) | Clinical Trial Compass
Not Yet RecruitingEarly Phase 1
Relationship Between Remimazolam and Etomidate in Induction of General Anesthesia
China125 participantsStarted 2025-06-12
Plain-language summary
In modern anesthesia practice, anesthesiologists often need to choose a combination of multiple drugs according to the specific conditions and surgical needs of patients, which can not only achieve more fine anesthesia management, but also improve perioperative safety and patient comfort. In clinical practice, anesthesiologists will use etomidate combined with a small dose of remimazolam for anesthesia induction to obtain more stable hemodynamics, prevent intraoperative awareness, and relieve anxiety.However, what is the best dose ratio of etomidate combined with remimazolam, the current literature does not give clear indicators.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
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What they're measuring
1
The ED50 value of etomidate in Group A
Timeframe: one week
2
The ED50 value of Remimazolam in Group B
Timeframe: one week
3
Group C D E: etomidate ED50
Timeframe: three weeks
4
Isoradiation pattern
Timeframe: 24 hours
5
drug correlation coefficient
Timeframe: 24 hours
Trial details
NCT IDNCT07012902
SponsorSecond Hospital of Shanxi Medical University