In modern anesthesia practice, anesthesiologists often need to choose a combination of multiple drugs according to the specific conditions and surgical needs of patients, which can not only achieve more fine anesthesia management, but also improve perioperative safety and patient comfort. In clinical practice, anesthesiologists will use etomidate combined with a small dose of remimazolam for anesthesia induction to obtain more stable hemodynamics, prevent intraoperative awareness, and relieve anxiety.However, what is the best dose ratio of etomidate combined with remimazolam, the current literature does not give clear indicators.
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The ED50 value of etomidate in Group A
Timeframe: one week
The ED50 value of Remimazolam in Group B
Timeframe: one week
Group C D E: etomidate ED50
Timeframe: three weeks
Isoradiation pattern
Timeframe: 24 hours
drug correlation coefficient
Timeframe: 24 hours