By InvitationNot Applicable

Associations Apnoea Hypopnoea Index (AHI) and Malocclusions in Growing Patients With Maxillary Constriction

Italy20 participantsStarted 2025-07-01

Plain-language summary

The aim of this prospective clinical study is to evaluate the association between the Apnoea Hypopnoea Index (AHI) and the type of malocclusion in pediatric patients with maxillary constriction. Malocclusion will be assessed through clinical examination and cephalometric analysis, which will also include an evaluation of the airway. Additionally, the study aims to assess potential changes in OSAS symptoms in patients undergoing orthopedic-orthodontic treatment with maxillary expansion. The AHI assessment will be conducted using nocturnal cardiorespiratory monitoring.

Who can participate

Age range6 Years – 12 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * mixed dentition * transversal skeletal constriction of the upper jaw, with or without cross-bite * Tonsillar grade I-III according to Mallampati classification Exclusion Criteria: * Previous orthodontic treatment * Previous adenoidectomy, tonsillectomy, or any surgical interventions of the upper airways; * Tonsillar grade IV * Presence of remote or familial pathologies; * Presence of syndromes or forms of disability

What they're measuring

Apnea-Hypopnea Index (AHI)

Timeframe: Baseline (T0) and after 1 year of treatment with RPE (T1)

Trial details

NCT IDNCT07009535

SponsorUniversity of Pavia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07

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