CompletedNot Applicable

Lumbar Spinal Stenosis and Central Sensitization

Turkey (Türkiye)81 participantsStarted 2025-06-17

Plain-language summary

Lumbar spinal stenosis (LSS) functionally limits individuals by causing pain in both the waist and the legs during activity and walking. Pain is, therefore, an important problem for patients. Pain lasts for years in LSS and thus becomes chronically persistent. As a result, persistent pain can cause sensitization due to a decrease in the pain threshold. This condition affects patients not only biomedically but also biopsychosocially. For this reason, various sleep disorders and mood disorders can develop in patients. Therefore, this study aimed to examine the relationship between central sensitization and pain, disability, sleep and depression in patients with LSS.

Who can participate

Age range

45 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with lumbar spinal stenosis by MRI, * The ages of 45-80, * Low back and/or leg pain that has persisted for at least 3 months * Volunteer to participate in the study Exclusion Criteria: * Patients who did not agree to participate in the study, * Those with a history of serious neurological diseases such as Parkinson's, hemiplegia, multiple sclerosis, * Those who had undergone surgery in the lumbar region within the last year, * Those with advanced joint disease in the lower extremity, * Those with malignancy in the spine, * Those who had a previous operation for the lower extremity, * Those who had a pain or disability in other musculoskeletal joints, * Those who had a psychological disorder or peripheral vascular disease * Those who had any concurrent serious medical condition, including sepsis or cancer * Those who did not cooperate well were not included in the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Central sensitization

Timeframe: Baseline

Pain severity

Timeframe: Baseline

Pain pressure threshold

Timeframe: Baseline

Disability levels

Timeframe: Baseline

Pain catastrophizing

Timeframe: Baseline

Sleep quality

Timeframe: Baseline

Depression

Timeframe: Baseline

Trial details

NCT IDNCT07001982

SponsorKarabuk University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-10-15

View on ClinicalTrials.gov More Lumbar Spinal Stenosis trials

Plain-language summary

Who can participate

Age range

45 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.