RecruitingNot Applicable

Correlation Study Between SMA Blood Flow Reactivity and Acute Gastrointestinal Injury in Critically Ill Patients

China80 participantsStarted 2025-06-01

Plain-language summary

This study aims to address the challenges of enteral nutrition support in critically ill ICU patients with varying gastrointestinal function. We'll use bedside Doppler ultrasound to monitor superior mesenteric artery (SMA) blood flow changes post - feeding, exploring its correlation with Acute Gastrointestinal Injury (AGI) and other hemodynamic indicators. Our goals are to identify the patterns of SMA blood flow changes, establish a predictive model linking SMA blood flow reactivity to AGI risk, and propose individualized enteral nutrition strategies based on intestinal hemodynamics. Through this innovative approach, we hope to enhance the safety of enteral nutrition, reduce AGI incidence, and improve patient outcomes.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion Criteria: * Adults aged ≥18 years and ≤80 years. * Admitted to the study with a expected stay of more than 72 hours. * Require initiation of enteral nutrition support. Exclusion Criteria: * Pre-existing severe gastrointestinal diseases. * Patients with gastrointestinal bleeding. * Patients with bowel obstruction. * Pregnant or lactating women. * Patients with contraindications to bedside Doppler ultrasound.

What they're measuring

feeding intolerance

Timeframe: From enrollment to the end of treatment at 3 days

Trial details

NCT IDNCT07001943

SponsorPeking Union Medical College Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-01

View on ClinicalTrials.gov More Intestinal Ischemia trials